Has anyone ever heard of a DAO Enzyme Supplement?  I was reading an article and this is what it stated:

"Introducing the first ever DAO enzyme supplement available in the US. It’s called Histame, and studies show it can provide enough supplemental DAO to inactivate even an extreme dose of exogenous histamine, bringing 80 to 90 percent relief of symptoms within just one hour. It’s a purified enzyme from pig kidneys, so it’s totally natural, and it has no side effects."

Just wondering if anyone out there had tried this stuff!

I tried HistDAO and at low doses (read: a few grains in some applesauce) it may have helped. Since I didn't seem to react at low doses I was NOT afraid to take a whole capsule (I only emphasize that because the usual MD response is...well, you must have been anxious   but when I took a whole capsule I reacted to it within 5 minutes. Wow- that was a doozy. And it was before I knew I had MCAS and knew to take Benadryl.  
I think to say it has no side-effects is dangerous. Everything has some sort of effect.. its more a matter of whether the effect is desired or not.  

That said. my allergist told me to throw it out. For MCAS it adds to our burden. I'm not sure about that... but since I stopped it months before it was no hardship to me.

Kelley