I had told my dental surgeon that because of a medical condition, I did not want him to give me nitrous oxide for my dental implant.  I have Postural Orthostatic Tachycardia.  Because of having POTS, he had a nurse assistant in there monitoring my vitals.

Anyhow, he didn't listen, and began giving me some through the nasal canula that was used to give me oxygen.

Within a few seconds, I said to the dentist, "What are you giving me?", because I could feel that I was getting weird. I also reminded him that I did not want anything.  (I had to have Novocaine, of course:I was having an implant.) He stopped giving me the nitrous.  I was happy.

It was making me feel ultra relaxed, like I didn't have a care in the world, and a bit "out of it".  I did not like being given it. It is probably what it feels like to be drunk on alcohol. I prefer feeling with it and I prefer having shorter recovery time.

Hi gnb,

There is a post under this area called "dental work"....it is on page 3 (on my screen) and posted by Doozlygirl.  It has some good information you may want to read if you have time, before your dental appointment.

I met with my dentist and had a consult the first time I went 'back' to him after my diagnosis (and after I became very symptomatic).

Have you ever used Ativan?  It is a benzo...but also a benzo blocker!  It's another pre-med I use that helps.  It also takes the "edge" off that anxious feeling.  I also had my dentist use carbocane with no epinephrine, and he didn't use any topicals (which contain alcohol which are mast cell degranulators).

It may not be just one thing that causes a problem. To me it was important to eliminate as many variables that cause mast cell degranulation as possible.  For some patients that can even include asking the office staff not to wash the instruments with vinegar!

Then, as you said, PRE-MED!!  good luck!