Do you mean headache pain... or scalp pain?  Or maybe pain from your skull?  The first two could definitely be mast cell symptoms... but masto bone pain is usually in areas with a lot of bone marrow (hips, legs).

Heather

Hello again, The pain starts out feeling like pressure but increases in severity then can lead to a migraine. I have tried every medicine preventative etc. over the past 20 years for migraines. The new daily pain I can't seem to get any doctor to grasp it. Sometimes it goes away at night so it may be somewhat orthostatic. I did doubt that it was mast cell related but wanted to check. I think it has more to do with dysautonomia. I have so many problems...digestion ,sometimes constipated, breathing, blood pressure, high ,low depends on the day, dizziness, trembles, feels like swollen lymph nodes at times, tender sore mouth, I do think I clench at night. Dr. Castells thinks with my 13 tryptase I have a mast cell problem but my symptoms seem more autonomic from what I have read from all of you. Try not to feel scard but it is hard. It is getting harder to stand for any length of time without nausea, weakness, feeling faint etc... Thanks for listening. I know I need to keep up hope

Joan and all,
Thank you so much for the encouragement. The last time I spoke with Dr. Castells she prescribed Ketotfin. I found a compounding pharmacy and will pick that up today, but admit I am afraid to try new medicine. I too think I may need to increase medicine to see benefits but I react so badly at times it is hard to increase. Last night I felt really bad and my BP was 82/57. I had the epi ready but didn't use it. I sipped cold water and got it back up a bit. I need to remember it takes trial and error and I need to keep trying. Thanks for listening.

I've had classic migraine since I was 15.  Often they come about when we are deficient in magnesium.  Try "Natural Calm" powdered magnesium.  Vitamin Shoppe and other health food stores sell it.  It also helps with sleep and regularity.