There are many MC patients who take aspirin and get relief from it.  Some research has shown that it can help a lot for those who can take it.

As for increasing meds, you have a couple of choices.  You can try adding very slowly, e.g., if a pill can be split, start by adding just a small amount.  you can do this if it doesn't have an enteric coating that keeps it from disintegrating until it's in the intestines, and if it's not time-released.   You can call the company or a pharmacist to ask.

Have you tried taking 3 doses, 8 hours apart?  Sometimes a double dose is too harsh taken at one time, but tolerable if taken hours apart. For many of us, meds don't seem to last the full 12 hours, so closer dosing is better.

Or, you can try to add a different medicine in the same class.  Do check these options with your doctor first, though.