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I think I just flunked Chromolyn 101 :( (Read 6185 times)
zippy890
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I think I just flunked Chromolyn 101 :(
10/13/13 at 13:14:14
 
I started low and slow on pure Chromolyn powder, 100mg/day, dissolved in warm water.  No gut upset, just a little more tired.  I did this for 3 weeks, and noticed I seemed to be getting more reactive, and my periph. neuropathy was getting worse.  I thought it would pass.  So, I bumped up to 200mg/ day in a split dose.   That when things went off the rails.  I got very tired.  My skin itched horribly, plus many other symptoms.   I stood it for one week, then I just couldn't take it any longer.  So I quit.   In 3 days, I felt 100% better.

Now, I have failed out on Ketotifen, and Chromolyn !

I have only two meds. after all this.   Allegra and Doxepin.   And I can only take a "certain" amount of those, or things go bad for me.  

I am still undermedicated.

Any suggestions from those more experienced than me ?   <s>

Todd in Tenn.
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Spartako
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Re: I think I just flunked Chromolyn 101 :(
Reply #1 - 10/13/13 at 18:25:45
 
Are you intolerant to salicylates? Because Chromolyn has structural similarities to salicylic acid and because of that some also react to Chromolyn.
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zippy890
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Re: I think I just flunked Chromolyn 101 :(
Reply #2 - 10/14/13 at 13:03:54
 
Yes, I believe I am reactive to salicylates.   Every time I try to take an aspirin, it bothers me really badly.

What to do ?   (:-.
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Britt
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Re: I think I just flunked Chromolyn 101 :(
Reply #3 - 02/08/14 at 11:38:08
 
I had no idea cromolyn shared properties with salicylates. Is this true?  If it is, it would explain why it makes me so sick. Ugh.
Does singulair share any salicylate properties?
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« Last Edit: 02/08/14 at 16:34:55 by Britt »  
 
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Spartako
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Re: I think I just flunked Chromolyn 101 :(
Reply #4 - 02/08/14 at 17:27:40
 
I react to salicylates in food and aspirin but have no problems with my singulair brand.
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Spartako
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Re: I think I just flunked Chromolyn 101 :(
Reply #5 - 02/08/14 at 17:35:24
 
I have not much idea about chemistry but the aspirin molecule and cromoglicic acid have some strong similaritys at one end.
Montelukast/Singulair is much more complex but it also has one end with OH-=O Atoms. Maybe this is what triggers mast cells?
Anyone here who understands more of chemistry?

http://en.wikipedia.org/wiki/Salicylate_sensitivity
http://en.wikipedia.org/wiki/Montelukast
http://en.wikipedia.org/wiki/Aspirin
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mountain girl
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Re: I think I just flunked Chromolyn 101 :(
Reply #6 - 05/15/14 at 01:04:40
 
Zippy..have you tried Quercetin?  There are a few threads on it you can read. Dr. Theo is a mast cell expert. He sells a formulation of Quercetin for mast cell patients that are very reactive. I do not take quercetin, but have heard some good things about it.

http://algonot.com/neuroprotek.php

http://www.mastcellmaster.com/

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033805

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