I have not tried the generic singular because I no long take it. Just didn't seem to do much for me and less is best is my meds policy!
I was told that legally they only have to put 20% of the original medicine in a generic and the rest can be filler.

Usually red 40 and yellows in inactive ingredients can cause issues.  Can you look up and list the ingredients here so we can have a look at them?

You should be about to go to the pharmacy and buy a few name brand ones to test.

Thank you Pam and Deborah! My gut feeling says it is the montelukast itself, but I also contemplate to try the original Singulair brand name and see what happens.

The ingredients of the generic named Tropaz:
lactose monohydrate
microcrystalline cellulose
croscarmellose sodium
hydroxypropyl cellulose
magnesium stearate
hypromellose
titanium dioxide
macrogol
iron oxide yellow
iron oxide red
iron oxide black

This is greek to me!    

You might want to ask your doctor about other leukotriene inhibitors.  There are several on the market.  Just like antihistamines, one might not be great for you, but a different one might be fine, that is, if the inert ingredients aren't the problem.

I actually had the same reaction to Singulair....was great at first for helping me breathe but I became incredibly irritable and aggressive on it after a couple weeks even on a small dose. (I had the same reaction to alot of the SSRI/SNRI meds) I have abnormally high catecholamine levels so maybe that is an influence regardless,  I didnt need to contend with that on top of my other symptoms so I stopped

Bren

Please Marcia, I ask that you be careful in the terms you give to some of your symptoms.   That shakiness is just that, jitters and not "seizure-like" feelings.   A seizure is a very different situation and it's a very serious reaction indicating either a lack of oxygen to the brain or sugar or some other kind of element which has caused your central nervous system to go into spasms.    The jitters which we can get, vibrations and even muscle spasms are not caused by and isquimia of some kind but are a direct influence of the very strong neurotransmittors upon our neuro-muscular system.  If you go telling your doctors about seizure-like symptoms you can mislead them.  

Has masto been connected to seizures?  No.  There is a case of epilepsy, but that's extremely rare and there are also cases of brain lesions due to lack of oxygen during syncope connected to anaphylaxis, but the seizures, if they were to happen are not a direct result or consequence of mastocytosis and our reactions.  

Now, why did the montelukast create this reaction?  Well, with some people it can be the inert ingredients causing the reacting and that shakiness is a prodome warning of imminant serious reacting and possible anaphylaxis.  What will stop it is taking some antihistamine be it benedryl or another kind of antihistamine.  

Due to all of us having very individual genetic makeups not all of us can tolerate large doses of meds right away and we must work up to it very slowly.  You may have taken 4 mg too many to start off with!   I can take 10 mg right from the start and it's an impressive improvement that it has given me.  So far I can handle any kind of medication at normal doses, but that could change in the future, we just never know.  

Lisa

Marci
I am curious in how you describe your seizures...as I have anaphylaxis like only one person ...that I have found in all my years..I am not an expert only know what happens to me...
I ...MY OPINION only is that some way my brain is affected as I can see, hear but cannot speak..and a few other things as well..
I am not up to date on the lastest research but long ago the only research concerning masto/brain had only been done on mice..but this could have changed.
redbird