I started out with 10mg/day of Pepcid, but then I switched to 150mg/day of Zantac.  Both are fine.  Right now I'm taking 300mg of Zantac twice a day plus 10mg of Pepcid Complete whenever I have heartburn.  It does help to have both an H1 blocker and an H2 blocker.  There are four different kinds of histamine receptors, but they're scattered all over your body and have somewhat different functions.  Give it a try and see if it makes any difference for you.  It's very unlikely to cause a negative reaction.

Heather

I take Ranitidine.    I've never taken any other type of H2 blocker so I don't know the difference between them.


As for H1, Allegra is my mainstay!   Love this medicine!  And apparently it loves me!   It's fast and effective and has turned around almost all of my crises.  Very rarely do I have to take a double dose or add any ranitidine or prednisone to turn it around - usually allegra does it all.


I also take Ketotifen and Polaramine as other H1 blockers.  Polaramine is not available in the US, but it's a very effective med as well - it crosses the blood/brain barrier as does Ketotifen, so I take these only at night.

Lisa

Thank you all for replying so quickly!  Everyone on this forum is so helpful and caring  I am thinking about trying the Zantac first, but I have Pepcid here too.  I always start off slowly and with a small dose.  I am SO sensitive to meds!   It always makes me nervous when I try any new med.  

I wonder if any H2 blockers would help with my asthma.  I can't tolerate Singulair, but I've been wondering if I very slowly titrate up with the children's chewables if my mast cell reaction to Singulair would go away or get worse.

Thanks,
Jenny