Hi all,
I have POTS/dysautonomia, with normal tryptase, methyllhistamines of 280 in my urine (over 200 is abnormal) and that was on a histamine restricted diet and forgetting to pee once in the jug.  
SO.....my flushing, crazy tachycardia episodes in 150's, hives, rashes, and eczema has all stopped since I have been on the histamine free diet.  I cheated on it recently to take my prostaglandin test and I started getting these episodes where I was all of a sudden hot all over and feeling faint, like I'm going to drop dead.  Absolutely terrible.  Hands and legs shake too.  Does that sound like an MCAD issue or is that my POTS?

In just a wee bit of denial over the MCAD thing, but it makes since since I have had chronic hives since I was a child.
I take a beta blocker everyday.  Does that cause mast cells to degranulate?  
THANK YOU ALL.

Hi sweetie

I understand the desire for it not to be mast cell activation . I have posted my experience in my first 4 months of serious reactions . I hope it shows how  i so wanted it to go away .

I am in a different place now , with good medication , MCAD , is controlable . Not curable , but controlable

The beta blocker information is available on the mastcytosis society web page as they discuss all forms of mast cell problems .

A good meds balance will control the effects of histamines - very fast heart rate . You are not alone in not having the breathing part of anaphylaxis and skipping to the low blood pressure phase . Only a few doctors understand this , thats why none have sussed this for you before The mast cell speclaists do Thats why you need one and not any old doctor

I am sorry if I was strong in my first message , sometimes there are things I need to say , that need to be clear

Josie xxxxxxxxxxxxxxxxxxxx