Pam,

I have MCAS and have been on Xolair for a year and a half. I get two injections (300mg) every two weeks. In the beginning I was sometimes in the ER twice a week with Anaphylaxis, now I am in the ER every 6-8 weeks with Anaphylaxis and have been on this cycle for over a year. I have to say I do not know if the Xolair is helping me much or not, but my doctor thinks that if I stop it I might go back to being in the ER twice a week with Anaphylaxis. So far I have not really noticed any bad side effects. I am also on cromolyn, singulair, H1's and H2's and prednisone, so it might be that I just experience so many side effects from these meds already, that I don't notice any from the Xolair. I believe it is worth a shot if you can get your insurance to cover it.

Mountain girl I totally agree with you.  I think the benefit would really have to out weigh the risk.

Crystal G...I am so sorry this is happening to you.  Do you know if you could be reacting to salicylates??  They are sneaky little devils that used to send me to the ER quite often.  Once i figured it out I am down to a few times a year. Also have you tried Singulair in your mix of meds...it seemed to help me more than I thought it would.