It definitely could.  I have the same problem... last year my liver was enlarged and my enzymes were off, so my GP sent me for an abdominal ultrasound.  "Fatty liver" was the conclusion.  Although I'm a little overweight, I don't drink and I'm not diabetic.  I contacted Dr. Molderings since one of his articles included a note about liver involvement in mast cell disorders... he told me it was probably fatty liver (even before I had the ultrasound results).

This year, only my ALT was elevated... the other two enzymes were fine.  Go figure.  Masto is so weird sometimes.  I've also had some mild kidney dysfunction that comes and goes.

Heather

I know!  I realize "fatty liver" is an accurate description, but sheesh.  Couldn't they name it after the doctor who discovered it or something?  My understanding is that for most people, fatty liver doesn't cause any major problems (especially when it's not caused by alcohol use), but you do have to monitor it just in case it gets really bad and leads to cirrhosis.  Yikes.  Oh... and if you needed another reason to avoid alcohol... here it is

I've heard "milk thistle" is good for detoxifying livers... but I haven't tried it and I can't say for certain if it's safe for masto people.  I would definitely tell your doctor first if a supplement sounds appealing.

Good luck with the gallstones too!  Have they bothered you, or did you find out about them through the ultrasound?

Heather

I also have a fatty liver, found by a CT scan.  I do not drink alcohol, (masto won't let me). They are not treating it. Good luck with the gall stones!