See article http://phoenixrising.me/archives/13083.  

Impressively, the article provides lots of background info on mast cells.  

Also touches on POTS, exercise-induced anaphylaxis, Chronic Fatigue, Dr Theo at Tufts.

Excellent article--thanks!

Both my partner and I have fibromyalgia and CFS/ME, and now she has also come down with SM, so it's interesting that they may be related.

Yes, these are related.  Dr. Ignacio Blanco of Spain is the doctor responsible for finding morphologically changed MCs in Fibromyalgia patients.  This finding totally rocked the masto world because up until this time NO OTHER known disorder caused the MCs to change their shapes.  So, this raised the question, are there other disorders which can do this, or is Fibromyalgia part of a MC disorder????!!!!!    Dr. Escribano is one of the very first to recommend Ketotifen to his patients with fibromyalgia!   He sees the connection and slowly others are agreeing.


Lisa

Doxepin is a good medicine for mast cell patients to try.  It blocks both H1 and H2 histamine as well as being a tricyclic antidepressant.  It can cause drowsiness, so it's important to learn how it affects you before driving or operating machinery.  I started out taking it at night, and it was great for sleep, too!