Very wise words, Redbird!!
I've had one of those moments where I wonder how I could possibly think these thoughts, they kinda scare me.....
Let's see if you all can follow for I really think they are crazy thoughts.
As you all know, our hormones when they go up and down will often take our emotions with them. Scientists have been studying the brains of men and women in regards to their emotions and they've found that a man thinks with one part and feels with the other and the two don't mix. This would explain why a man can keep so frustratingly cool under pressure which would kill an elephant! This is why they can turn it off and on at a whim! Yet what they found when they studied women was that we're a mess - we think and feel with both sides of our brains and it explains why we can't so easily just "turn it off".
Now, when we study histamines and their affects on the brain, they have seen that it gets released throughout the entire brain and that the mast cells are closest to the blood vessels and the nerves. So, when we degranulate within our brains, our most important receptors are absolutely flooded with those mediators, which explains the brain fog we get! It also explains a heck of a lot of other weird stuff, like our emotions. We get an inundation of chemicals! So, this would explain a lot of the feeling of doom as well as even crying and being overly emotional and aggitated. I've had it where I feel like I'm going to crawl right out of my skin, not because of any tingling or anything but just because I feel so very anxious and uncomfortable within my body, emotionally wise, when I'm doing heavy duty reacting!
So, this may explain a great deal about why you could have bouts of crying. Yet, like Jilly has said, she gets bouts of the boo hoos with Zyrtec and this would be a chemical reaction creating this. Prednisone can do this as well as other meds. It may be the mast cells, but then it may be some other reaction going on to those meds. There are medicataions which are KNOWN for producing suicidal thoughts. Well, nobody's going to be thinking suicide if they've got a case of the giggles are they???? Make the connections yourself. So, in this case, you really must examine the medication even though nobody else may have responded that way. As we all well know, we are all so different with this disease that the trick is to find someone doing something similar to you!
Now, Redbird, you are in your own category mainly due to your age. When we study the body and how it ages, you need to consider masto and it's interaction. As we know, the blood vessels become weaker as we age. Well, has anybody studied the neurological system and how it bears up over the years? I rather think that the myelin sheath may get thinner and perhaps the nerves themselves get more sensitive. I don't know, but it sounds reasonable to me.
So, if we take that thought in mind, it is well known that as a person ages, they have less ability to control their emotions. They are known to return to a more childlike ability to keep their emotions in check and this is why you will usually find that generally the elderly can be grouped into two groups, the cantankerous and the sweetly tempered. I've heard someone say that after a certain age, it's not that the person's personality has changed, but that they have lost their ability to cover up what they really are and so the truth comes out.
Well, I'm not one to study the elderly, so I really don't know if this if true or not, but it sounds pretty good to me anyway.
But, when if you take these two things, that of the losing the ability to control your emotions along with the possible aging of the nervous system, I think that this would explain either bouts of anger or crying which are indeed seen easily in people of this age.
Now, let's put the mediator release of mast cells on top of all of this, then what kind of mess have we got here??? hmmmm????? MESSY, MESSY, MESSY!!!
All I can say is I think they'd better consider locking me up in a nice, pretty padded room by the time I get 75, I think, for I have a feeling that not only will my nerves not manage to handle the slightest sounds or aggitation, but I'll probably take off the heads of anyone within sight or sound of me!!!