I hope someone can help me with this.  I started Singulair low dose 5mg two weeks ago, and upped it to 10mg yesterday.  The side effects (mostly worsening of my symptoms but some new sx like the anxiety/irritibility/depression/anger and can't sleep) started immediately and have been awful the whole time so I figured I should stop.  

But these problems might just be temporary.

How do I know when to say that SIngulair is not for me?  I don't want to give it up too early, but I also don't want to make my health as bad as it is at the moment or do anything that might have longer-term consequences.  I'm really having trouble coping with Singulair's effects at the moment and only just hanging on to sanity.  My doctor doesn't know anything about mast cell related conditions and in any case is not accessible for another two weeks.

Is this written up somewhere or does anyone have any advice?

Thanks.  My doctor really has no idea about Singualair and likely benefits or problems with MCAD.  When I reported after 10 days he first suggested I should stop, then decided I should increase the dose since there is nothing else available.  It gets into the blood very quickly but I don't think this is the answer to how long it might cause bad reactions.  As you say it won't suit everybody but I just don't know how it normally works with other people and when to give up on it.  Since you had no problem with it from the beginning, maybe my bad experience tells me it won't work for me.

Is there an alternative to Singulair with similar benefits.  I just stopped it again after a month trial due to it causing stomach upset.  After a month of feeling like I was going to be sick all the time, I finally decided to give it up again...after a week, tummy so much better.  I have tried it multiple times and added extra prilosec, my stomach just revolts on it.  So....is there an alternative in a similar med class?  Of course  I already do zyrtec and zantac.

I tried Singulair and only could stick with it for a few days.  Bothered me a LOT.  Felt very ill on it.  It was just way too strong for me.

I am a lightweight for meds and now am on Loratidine (Claritin), as that seems to be the only thing I can take that makes me feel better.

jr:
I as well as future had issues when I first went back to singulair, but mine was different, no nightmares or insomnia. But I take my zrytec
at night & added singulair at night & in the morning had trouble waking up without a drug hangover. Changed to taking singulair in morning issues went completely away, so like future in the morning works well for me. Our bodies are so strange the time taking a med can effect our ability to take it. Where you taking it each time you tried at the
same time of the day or maybe on empty stomach. If so maybe switch time & try ,or try zyflo, as for our standard treatment protocal docs use 1 or the other.
mikev