Hi all. I have been battling severe depression for the last month and the doc has put me on an SSRI (Lexapro). I know they are 'bad' for us mast cell types but I really need to give it a go or at least try another if this fails.

I am having horrible diarrhea though - does anyone know if we mast cell types can take Immodium or an Acidohpholus type supplement? Both are recommended on the Net for this type of reaction.

Immodium is also called loperamide. If anyone can recommend another diarrhea type treatment I am all ears as have not been able to leave the house for two days which is quite hard with a three year old!


Thank you all.

Hi Heather

I am taking ketotifen already and ranitidine. I don't think it is a mast cell reaction to the SSRI per se - just a side effect - and what has been suggested is Immodium or acidophlous. I just don't know if eitehr of those suits masties? Thank you for the quick reply.

Hi Miss Marple,
I'm sorry you are struggling with depression ,  I've also been pretty down lately. Sometimes maintenance of these symptoms is so frustrating! I spent a lot of years being able to manage with not a ton of people knowing whats wrong with me, now It's just not like that anymore, I'm having to admit/acknowledge limitations and it's frustrating the (*&*&&& out of me.  I personally can't wait for menopause!!! I do much worse that time of the month. I'm going to have a party when it's over!! Ok, back to your subject..... I personally did react horribly to Immodium,( but I have a history of terrible medication reactions) I've struggled with very chronic diarrhea for a long time. I can easily go through a big roll in a day. The things that helped me the greatest were elimination of dietary triggers/intolerance's/allergies, I've got a ton and Allegra (fexofenadine) yeah that's right fexofenadine! It blew my mind when I improved once I started it! (again had trouble with one brand and did wonderful with another) then adding the rantidine that I finally found and it has helped too. I credit allegra to my first formed poo in a decade!  Acidophilus, sure it's good stuff , however it's usually in a base of lactose /dairy and if you have a problem with what it's in forgetaboutit! I'd rather see you get an overall probiotic with much more than acidophilus, the prob is finding one you tolerate! I believe Joan tolerates align, PB8 is another good one, If I recall you are overseas so you may be doing some research . Hit up some health food stores and see what they have, see if there are samples you could try then you are not out of the expense of a bottle if you don't do well. If you tolerate dairy then get the natural whole yogurts they are full of good stuff.  Gut health is very important to overall health, the world is slowly coming around in that arena. My diarrhea is  histamine/mast cell based if it wasn't Allegra wouldn't have helped enormously. So your key could be upping your antihistamines. Also dietary changes to "thicker foods" you tolerate
oatmeal, protein, it might be a tad bit slower to work but may bother you less! Also your "intestines" may adjust to your new med and your constitution could be right back to normal! Hugs, Kiddo you have a three year old so you get some rest when that child is ,  you hear! This was a random scatterbrained note from Sandi!