Lisa:
Well my ketotifen expirement has ended for now. I know all us have strange & very different masto's but mine is always challanging. I started slowly but upped it very quickly to the 1mg and was going to up to 2mg in the future. I noticed when I first started taking almost instantly my upper body skin discomfort seemed to lessen but my feet sort of tingled more. I just thought it was me being sensitive or something and that the upper body was the real thing. My feet kept slowly getting worst, but the upper body was doing fine so I continued taking it. The weekend before last my feet went crazy. They turned beet red like they used to do before I was diagnosed & I could hardly walk the pain was so bad. The next day my hands did the same thing beet red  and my arms started hurting, so I looked hard to see if it could be anything else that was going on with me and made for me a very, very difficult decision. To stop. It has now been about 10 days &  my hands are back to normal & feet haven't completely returned to where they were but almost. This decision to stop was very, very difficult. from what I read for people with more systemic issues than gastro issues, like me, ketotifen should have been the better medicine. I was not taking the generic, either,  but the actual Zaditan from England. To say it's  depressing is to put it mildly. My wife who does support me once again had the comeback of don't you ever get tired of looking for that magic medicine that will make you better & I know my doctor who I practically had to beg to give me the prescription will although he may not say it will feel the same as my wife. So right now my body is slowly going back to where it was which is the good thing, but I'm in utter disbelief of what happened. I had read of people not being able to take it as it made them too tired or they gained lots of weight but to trigger a major mast cell attack is unbelievable. I hope this note doesn't keep other people from trying it as I know it works for a lot of people. I hope to when things get settled down completely try again just to prove it. Do you or anyone else have any idea of what could have happened?
Thanks
Mike V

Josie:
Thanks for your response. It does make sense. I know that I have a serious problem with sulphates, as I believe that my masto was a result of taking glucosamine, chrondrotin & MSM for a period of over 5 years. Looking back at those 5 years. I now can see a gradual skin sensitivty problem until the first major episode which started with the burning feet. At first I & my docs thought it was neuropathy, until it went full systemic and that's when my search finally lead me to a doc who diagnosed me with masto. Thus I'm going to do more research into the area that you pointed me to. You don't know how much I appreciate your caring about my condition.
MikeV

Mike, so sorry to hear about the ketotifen reaction! Arggghhhh so frustrating isn't it! I just got the zaditor eyedrops you told us about. I was thinking that doesn't bother you however it's a tiny amount, again as Josie stated it very well could be an inert ingredient! again so sorry and I understand the medication frustration! Grrrrrrr!

Everbody:
Thanks all of you for the concern. I think Josie maybe on the right track with the ingrediants mixed with ketitofen. I know I have issues with sulphates & I never noticed that corn starch which as Josie says has a high sulphite concentration. Anyway I have never shocked, I guess there could be a first time but the extreme flushing of my feet always means something bad is going on. And Lisa I really don't blame my wife. I would be tired of living with me too. And your advice on singular I'm taking. In looking at the ingrediants in Zyflo and singular it makes no sense to keep the zyflo. On top of it in St Louis the allergy rating is off the chart so not a good time of year for me anyway. Thanks to all my masto friends for their support and again I think Josie is right about the liquid ketotifen, when thinks quiet down I'm going to try to get a script for it, too  many people have good luck with ketotifen and with me being systemic it should work better than gastrocrom.
Thanks
Mike V

Lisa:
Thanks for your thoughts. I'll do some research into both especially the Rupafin. Right now just trying to get back to where I was, such is all of our lives with masto, but without trial, even though error often occurs, sometimes success does happen & the errors although tremendously deflating help us in my opinion better explore our own version of masto  I've started singular & elimanated zyflo, with all it's fillers, so for now no issues there. And with Josie's help trying to eliminate as many hidden sulfites as possible. Right now my skin is fairly well back to normal, but the feet are the issue. Have elimnated using any products with alcohol or menthol in them to cool my feet but still a lot of flushing, which for me is more pain. Also eliminated any cold water to try to cool them down. Had noticed in the past when tried this they would get purple & that's what's  happening now so no cold water on them. And to Heather my thoughts are with you, how sad doing something so wonderful as giving your daughter a great birthday party turns into an episode for you. Hope you get back ok soon. And to Sandi, did the eye drops help you? If not although it is a script & not cheap Pataday really helps my eyes a lot.
Mike V