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http://mastcelldisorders.wallack.us/yabb/YaBB.pl New Mast Cell Research, Studies, and Trials >> New Mast Cell Research, Studies, and Trials >> Nickel allergy, Kounis syndrome and intracardiac metal devices http://mastcelldisorders.wallack.us/yabb/YaBB.pl?num=1309113334 Message started by Riverwn on 06/26/11 at 07:35:34

Title: Nickel allergy, Kounis syndrome and intracardiac metal devices
Post by Riverwn on 06/26/11 at 07:35:34

Int J Cardiol. 2010 Nov 19;145(2):364-5. Epub 2010 Mar 6.

Nickel allergy, Kounis syndrome and intracardiac metal devices.

Almpanis GC, Tsigkas GG, Koutsojannis C, Mazarakis A, Kounis GN, Kounis NG.
Abstract

Metal-induced allergic reactions are not rare in every day practice but nickel, cobalt and chromium are the most common offenders. Other metal anions and metal alloys represent also emerging causes for hypersensitivity reaction in humans. The metal struts of endovascular and intracardiac devices are usually alloys containing nickel and constitute causes for allergic reactions with possible intracardiac and intracoronary mast cell activation resulting in the Kounis hypersensitivity coronary syndrome. Newer intracoronary stents avoid nickel thus making them less allergenic. It is advisable that, before any device implantation, careful history of any metal allergy should be taken and efforts should be made for the development of new devices with better biocompatibility.

Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

http://www.ncbi.nlm.nih.gov/pubmed/20207036

Title: Re: Nickel allergy, Kounis syndrome and intracardiac metal devices
Post by Susan on 06/26/11 at 10:37:46

I will have to send this to my cardiologist. He wants me to have a patch put on my heart, as the opening between the ventricles is shunting blood. When I found out the patch has a nickel-titanium framework, I refused the surgery. I can't believe they don't have any other option, given how many people are allergic to nickel.