Mast Cell Disorders Forum

Mast Cell Disorders Forum
http://mastcelldisorders.wallack.us/yabb/YaBB.pl New Mast Cell Research, Studies, and Trials >> New Mast Cell Research, Studies, and Trials >> Anaphylaxis and Hypersensitivity Reactions http://mastcelldisorders.wallack.us/yabb/YaBB.pl?num=1299897346 Message started by Starflower on 03/11/11 at 14:35:46

Title: Anaphylaxis and Hypersensitivity Reactions
Post by Starflower on 03/11/11 at 14:35:46

Dr. Castells is the editor of a brand new book (2011) titled, "Anaphylaxis and Hypersensitivity Reactions." I have SERIOUSLY been tempted to buy this book... even though it costs more than $200. I own a lot of books... I've just never paid that much for a single book before. Tonight I found out that instead of purchasing the actual book, my university decided to purchase a permanent electronic link!! This means I can read the book anytime I want for free!!!!!!!!

I feel like a kid in a candy store right now [smiley=2vrolijk_08.gif]. I am such a geek!! In a moment I'll post the table of contents.

Heather

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Starflower on 03/11/11 at 14:55:24

TABLE OF CONTENTS

1. Definition and Criteria for the Diagnoses of Anaphylaxis

2. An Epidemiological Approach to Reducing the Risk of Fatal Anaphylaxis

3. Pathophysiology and Organ Damage in Anaphylaxis

4. Mast Cells: Effector Cells of Anaphylaxis

5. Basophils in Anaphylaxis

6. Protease Mediators of Anaphylaxis

7. Aspirin and NSAID Reactions: Diagnosis, Pathophysiology, and Management

8. IgE-Dependent and Independent Effector Mechanisms in Human and Murine Anaphylaxis

9. Food-Induced Anaphylaxis

10. Antibiotic-Induced Anaphylaxis

11. Anaphylaxis During Radiological Procedures and in the Peri-operative Setting

12. Hymenoptera-Induced Hypersensitivity Reactions and Anaphylaxis

13. Idiopathic Anaphylaxis

14. Exercise-Induced Anaphylaxis and Food-Dependent Exercise-Induced Anaphylaxis

15. Mastocytosis and Mast Cell Activation Syndromes Presenting as Anaphylaxis

16. Anaphylaxis in Mastocytosis

17. Flushing and Urticarial Syndromes Presenting as Anaphylaxis

18. Pharmacologic Managment of Acute Anaphylaxis

19. Drug Densensitization in the Managment of Allergy and Anaphylaxis to Chemotheraputic Agents and Monoclonal Antibodies

20. Rapid Densensitizations for Antiobiotic-Induced Hypersensitivity Reactions and Anaphylaxis

21. Induction of Tolerance for Food-Induced Anaphylaxis

22. Management of Anaphylaxis: Relevance of Causes and Future Trends in Treatment

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Starflower on 03/11/11 at 14:55:54

Where do I start?!?!? [smiley=2vrolijk_08.gif]

:D :D :D :D

You know who...

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by ruth on 03/11/11 at 15:12:40

Those smilies say it all! I'm really excited for you, this looks like an amazing resource, and this community will get the benefit of you having access to it, as well as the ability to understand and explain some of it in lay terms. Thanks for what you give here :)

Ruth

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Lisa on 03/11/11 at 15:30:45

I'm sooooo Jealous!!!

Good for you, Heather! That's just great news!!! Read bunches for me please!

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Joan on 03/11/11 at 19:07:31

What are protease mediators of anaphylaxis? That's either a new one to me or "protease" has other meanings.

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Starflower on 03/12/11 at 01:12:55

Hi Joan,

This idea is somewhat new to me too...

Proteases (also known as peptides) are enzymes that the body uses to regulate functions such as digestion, inflammation, coagulation, and complement activation. Mast cells and basophils contain several types of proteases that are unique to those cells (not found in other types such as eosinophils, macrophages, etc...). These include chymase, cathepsin G, tryptase, carboxypeptidase A3, and cathepsin C. As you already know about tryptase, these enzymes are currently being used as markers of mast cell burden/activity. However, there's no such thing as a tryptase "antagonist" or "blocker" because researchers are still trying to figure out what exactly these proteases do inside the body! There's no point in blocking something that's not causing harm or even serving a helpful function.

Heather

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Joan on 03/12/11 at 18:12:58

Thanks, Heather. Will look forward to hearing more about what you're reading!

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Josie on 03/13/11 at 03:05:41

Hi heather ,

WOW , I am sooooooooooooo excited to . I await your imput with bated breath xxxxxx I so wish I could read it xxxxx

Josie xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Sandi on 03/13/11 at 16:59:42

Yeah I want it too! Reminds me something I wanted to tell Ruth with the teenage son!!! Going there now!

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by Riverwn on 03/17/11 at 08:34:37

I found this while surfing the web to find the book cheaply!!
[b]Read it ALL online!![/b]
http://www.springerlink.com/content/978-1-60327-950-5#section=829173&page=1

Title: Re: Anaphylaxis and Hypersensitivity Reactions
Post by summerfields on 03/18/11 at 03:10:56

SpringerLink above: I had wondered why certain pages were available but not others, then was particularly frustrated when I wanted to read the chapter on aspirin sensitivity. I gather one has to pay $25 to access the whole book. Better than buying it, but I can't do it now.

Looks like a great resource, though, wish all of our doctors would read it!